Typical Signs of Illness ------------------------ A sick box turtle may not eat and may lose weight. Swollen and/or runny eyes, nasal discharge, swollen ears, lumps or swellings, wounds to the shell, increased water consumption, diarrhea, extreme lethargy, weakness and coma are other signs of illness. Subtle changes in behavior and the turtle's routine often signal the onset of illness. It is at this stage in the course of an illness that a box turtle should be presented to a veterinarian. A thorough physical exam and a laboratory work-up (blood and/or bacteriology tests) can be performed to diagnose and properly treat the problem.