Canine Distemper ---------------- Ferrets are highly susceptible to canine distemper. The initial signs of the disease appear 7-10 days after exposure to the virus and include inappetence as well as a thick mucus and pus-laden discharge from the eyes and nostrils. A rash commonly appears under the chin and in the groin area 10-12 days following exposure. The foot pads become greatly thickened. This disease is considered 100% fatal, with infected ferrets dying 3-3 1/2 weeks after initial exposure. Prevention of this disease should be an absolute priority because treatment is useless. Kits should first be vaccinated against canine distemper at 6-8 weeks of age (4-6 weeks of age if kits are from unvaccinated mothers). A booster vaccination is essential 2-3 weeks later. Yearly boosters are recommended thereafter.