Sexing ------ Sexually mature mice and rats must be properly paired to breed successfully. A single male mouse may be included in an enclosure with one or more female mice without difficulty. Including more than one male mouse in this situation invites fighting between them. By contrast, more than one male and female rat may be housed together for breeding purposes within the same enclosure without aggressive displays. Sexually mature male mice and rats usually exhibit a prominent scrotum. Sexually mature female mice and rats usually exhibit a prominent double row of nipples. Furthermore, the distance between the rectal opening and the penis of the male is greater than the distance between the rectal opening and the urinary opening of the female in both mice and rats.