Housing ------- Proper housing is a major factor in the maintenance of healthy mice and rats. The psychosocial well-being of the animals must be a primary consideration. Mice and rats can be housed within enclosures made of wire, stainless steel, durable plastic or glass. The last three materials are preferred because they resist corrosion. Wood and similar materials should not be used in construction of enclosures because they are difficult to clean and cannot withstand the destructive gnawing of rodents. The construction and design of the enclosure must ensure that the resident(s) cannot escape. Furthermore, the enclosure must be free of sharp edges and other potential hazards. The enclosure must be roomy enough to allow the rodents to pursue normal movement and breeding activity, if the latter is desired. Visual security (a place into or under which the rodents can retreat for privacy) should be provided, as well as exercise wheels for optimum mental and physical health. Rats, in particular, tend to be burrowers and seem to enjoy hiding under things for extended periods. Enclosures should be easy to clean, well lighted and adequately ventilated (see Vital Statistics for preferred temperature and relative humidity ranges). Bedding must be clean, nontoxic, absorbent, relatively dust-free and easy to replace. Shredded paper, wood shavings and processed corn cobs are preferred bedding materials. Tissue paper or cotton are often supplied to breeding rats for nest-building material. Pet mice and rats seem most comfortable when they are spared exposure to excessive noise, needless excitement and confusion, and other similar or perceived stresses. Sudden environmental temperature changes should also be prevented because pet rodents do not tolerate them well. Mice can be aggressive toward one another, so great care should be taken when housing more than one mouse within the same enclosure. Newly assembled male groups and new males entering established territories, in particular, are likely to fight, so it is wise to always house male mice separately. Domestic female mice seldom fight unless they are defending their nests. Rats are more communal and, in contrast to mice, several males and females may be housed within the same enclosure, provided that it is roomy enough. In fact, young rats are raised by the group and nursing responsibilities are shared between females. These nursing females may fight among themselves. Males may occasionally bother the young, but aggression between rats is generally infrequent (in contrast to mice). Every effort to prevent the escape of pet rodents should be made because they can be a tremendous nuisance when allowed the run of the house. Escaped rats tend to eventually return to their enclosures, whereas escaped mice tend to fend for themselves within the home and do not return to their enclosures.