Mite Infestations (Mange) ------------------------- A mite similar to the scabies mite of people causes serious infestations in pet guinea pigs. Mites are microscopic, spider-like organisms that live within the outer layers of the skin. They usually cause intense scratching and significant hair loss. Some cases without scratching have been reported. Some guinea pigs are so miserable because of the infestation that their constant scratching produces serious wounds. They may run wildly or in circles and may occasionally even have convulsions. A veterinarian must do a number of scrapings of the skin to confirm the diagnosis. Successful treatment consists of 1-4 injections of a specific drug (ivermectin) 10-14 days apart. Any wood shavings within the enclosure should be replaced by white paper toweling during treatment to help make the patient more comfortable. Mites can only be transmitted by direct contact between infested and uninfested guinea pigs. Therefore, pet guinea pigs are very unlikely to harbor these parasites unless they are recent acquisitions that were previously in contact with mite-infested guinea pigs. Established pet guinea pigs could also be infested by being placed in close contact with new, infested guinea pigs. Guinea pig mites do not parasitize people.