Blister Disease --------------- Blister disease is common in many captive reptiles. It is most often associated with the maintenance of these animals in damp, filthy environments. The first sign is usually a pink to red appearance of the bottom-most scales. Later, these scales become swollen and infected by bacteria and fungi. At the first suspicion of this disease, you must seek veterinary help. Treatment involves use of topical and injectable antibiotics. Furthermore, the underlying sanitation and hygiene problems must be corrected. Blister disease is preventable if you are aware of it and if the enclosure in which captive snakes are housed is kept dry and scrupulously clean.