Rheumatoid Arthritis -------------------- General Information Rheumatoid arthritis is an uncommon joint disease that usually affects small or toy breeds of dogs. It can affect dogs as young as 8 months of age. The disease first appears as lameness that changes from leg to leg, with swelling of the affected legs. Within weeks to months, the disorder settles in particular joints. Radiographs (x-rays) of involved joints show destruction of bone. As the disease progresses, the joints may dislocate and appear deformed. The cause of rheumatoid arthritis is unknown, but the disease probably results from a defect in the immune system. Important Points in Treatment 1. Rheumatoid arthritis is a difficult disease to treat, and lifetime treatment is usually necessary. The condition may improve dramatically at first, but as time passes, it may become unresponsive. Very potent anti-cancer drugs are often used in treatment. This necessitates close monitoring of the dog's general health with periodic laboratory tests. 2. Give all the medication as directed. Call the doctor if you cannot carry out the prescribed treatment. 3. Activity: The pain of rheumatoid arthritis naturally restricts activity. Do not force your pet to exercise or allow it to jump from furniture, steps, etc. 4. Special instructions: Notify the Doctor if Any of the Following Occur: * Your dog's signs worsen. * Your dog's signs recur after apparent recovery. * Your dog's general health changes.