Acanthosis Nigricans -------------------- General Information Acanthosis nigricans is a skin condition that usually appears first in the underarm area of the front legs. It begins as a small, oval brown spot that gradually darkens and spreads to the front legs, chest, lower sides, abdomen and hind legs. As the disease progresses, the affected skin becomes darker and thicker and begins to fold. The skin has an unpleasant odor and feels greasy. Primary acanthosis nigricans occurs almost exlusively in Dachshunds and often appears in young dogs. The condition is probably inherited, and its cause is not well understood. Secondary acanthosis may occur in any breed and is associated with (1) friction in the underarm areas due to obesity or heavy skin folds, (2) hormonal imbalances of the thyroid, adrenal or sex glands, and (3) hypersensitivity (allergic) reactions. Important Points in Treatment 1. Primary acanthosis nigricans is controllable but not curable. Treatment is usually necessary for your dog's whole life. With secondary acanthosis nigricans, the outlook depends on whether the underlying cause can be corrected. 2. Laboratory tests are often necessary to diagnose the condition and monitor its progress during treatment. 3. Medication: All medication must be given as directed and on schedule. Notify the doctor if you cannot give the medication as directed. 4. Diet: In overweight dogs, the diet must be adjusted to promote weight loss, thereby reducing frictional irritation of the skin. When obesity is part of the underlying cause of acanthosis, control is impossible without adequate weight loss. The doctor will discuss a proper feeding schedule with you. 5. Bathing instructions: Notify the Doctor if Any of the Following Occur: * Your dog's skin and coat do not improve after 4 weeks' treatment. * Your dog's condition worsens. * You cannot medicate your dog as directed.