Sertoli-Cell Tumors ------------------- General Information Sertoli-cell tumors generally occur in male dogs over 5 years of age, but occasionally are found in younger dogs. Usually the tumor develops in a testicle that is not descended into the scrotum. However, a testicle within the scrotum may be involved also. These tumors generally do not spread to other areas of the body. Female hormones (estrogens) are produced by about 15% of the tumors in normal testicles, 50% of the tumors in testicles located in the groin, and 70% of the tumors in testicles located in the abdomen. Female hormones cause the development of female characteristics, such as enlarged mammary glands, swollen skin enclosing the penis, localized hair thinning, and reduced penis size. Dogs with Sertoli-cell tumors may also be sexually attractive to other male dogs. Important Points in Treatment 1. The only effective treatment is surgical removal of the testicles (castration). Signs disappear within 1-3 months. 2. The following pertains to dogs whose surgery has been completed and are being released to go home: * Diet: Ordinarily no special diet is required. * Activity: Only moderate on-leash exercise is allowed until the sutures (stitches) are removed. Then normal activity may be resumed. * Environment: Keep your dog in the house and frequently change the bedding until the stitches are removed. Your dog will be evaluated for suture removal in ____ days. Notify the Doctor if Any of the Following Occur: * Your dog chews out the stitches or opens the incision. * The incision becomes red, hot or swollen, or oozes fluid or pus. * Your dog experiences painful urination, or there is blood in the urine. * Your dog's general health changes.